تفاصيل الوثيقة
نوع الوثيقة |
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مقال في مجلة دورية |
عنوان الوثيقة |
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DARPins Bioengineering and its Theranostic Approaches: Emerging Trends in Protein Engineering. DARPins Bioengineering and its Theranostic Approaches: Emerging Trends in Protein Engineering. |
لغة الوثيقة |
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الانجليزية |
المستخلص |
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The therapeutic significance of bioengineering proteins has increased dramatically as a new generation of pharmacological drug with a great potential in medical treatment. Protein engineering has improved the use of new non immunoglobulin affinity proteins. The designed ankyrin repeat proteins abbreviated as DARPins is a classical example. These molecules have smaller structural size, unlike immunoglobulins, but similar target affinity is of great significance. Such molecules get more binding specificity and greater thermodynamic stability. These attributes made DARPins a favorite player in diagnostics and therapeutics of cancer. How DARPins are improved into vigorous and versatile scaffold for binding protein and selected by ribosome and phage display along with related aspects is discussed in this review. |
ردمد |
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1381-6128 |
اسم الدورية |
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Current pharmaceutical design |
المجلد |
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23 |
العدد |
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11 |
سنة النشر |
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1437 هـ
2016 م |
نوع المقالة |
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مقالة علمية |
تاريخ الاضافة على الموقع |
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Tuesday, July 18, 2017 |
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الباحثون
M. Rasool | Rasool, M. | باحث | دكتوراه | |
A. Malik | Malik, A. | باحث | دكتوراه | |
M Hussain | Hussain, M | باحث | دكتوراه | |
KA Haq | Haq, KA | باحث | دكتوراه | |
K Butt | Butt, K | باحث | دكتوراه | |
MAB Ashraf | Ashraf, MAB | باحث | دكتوراه | |
MI Naseer | Naseer, MI | باحث | دكتوراه | |
M Asif | Asif, M | باحث | دكتوراه | |
R Shaikh | Shaikh, R | باحث | دكتوراه | |
MZ Mustafa | Mustafa, MZ | باحث | دكتوراه | |
Q Alam | Alam, Q | باحث | دكتوراه | |
G Rasool | Rasool, G | باحث | دكتوراه | |
W Ahmad | Ahmad, W | باحث | دكتوراه | |
A Haque | Haque, A | باحث | دكتوراه | |
MA Kamal | Kamal, MA | باحث | دكتوراه | |
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الرجوع إلى صفحة الأبحاث
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